Melvin Evers: search on Z-Library

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1

AAV5-miHTT gene therapy demonstrates broad distribution and strong human mutant huntingtin lowering in a Huntington disease minipig model

Evers, Melvin M., Miniarikova, Jana, Juhas, Stefan, Vallès, Astrid, Bohuslavova, Bozena, Juhasova, Jana, Skalnikova, Helena Kupcova, Vodicka, Petr, Valekova, Ivona, Brouwers, Cynthia, Blits, Bas, Lube

Journal:

Molecular Therapy

Year:

2018

Language:

english

File:

PDF, 4.68 MB

english, 2018

2

Development of an AAV5-based gene therapy for Fabry disease

Liu, Ying Poi, Liefhebber, Jolanda M.P., van der Zon, Tom, Paerels, Lieke, Ferraz, Maria J., Ottenhoff, Roelof, Zancanella, Vanessa, Au, Betty, Kuo, Chi-Lin, de Vries, Carlie J.M., Evers, Melvin M., K

Journal:

Molecular Genetics and Metabolism

Year:

2020

File:

PDF, 333 KB

2020

3

Rescue of spinal muscular atrophy mouse models with AAV9-Exon-specific U1 snRNA

Donadon, Irving, Bussani, Erica, Riccardi, Federico, Licastro, Danilo, Romano, Giulia, Pianigiani, Giulia, Pinotti, Mirko, Kostantinova, Pavlina, Evers, Melvin, Lin, Shuo, Rüegg, Markus A, Pagani, Fra

Journal:

Nucleic Acids Research

Year:

2019

Language:

english

File:

PDF, 5.57 MB

english, 2019

4

Potent and sustained huntingtin lowering via AAV5 encoding miRNA preserves striatal volume and cognitive function in a humanized mouse model of Huntington disease

Caron, Nicholas S, Southwell, Amber L, Brouwers, Cynthia C, Cengio, Louisa Dal, Xie, Yuanyun, Black, Hailey Findlay, Anderson, Lisa M, Ko, Seunghyun, Zhu, Xiang, van Deventer, Sander J, Evers, Melvin

Journal:

Nucleic Acids Research

Year:

2019

Language:

english

File:

PDF, 11.81 MB

english, 2019

5

Translation of MicroRNA-Based Huntingtin-Lowering Therapies from Preclinical Studies to the Clinic

Miniarikova, Jana, Evers, Melvin M., Konstantinova, Pavlina

Journal:

Molecular Therapy

Year:

2018

Language:

english

File:

PDF, 1.46 MB

english, 2018

6

Antisense-Mediated RNA Targeting: Versatile and Expedient Genetic Manipulation in the Brain

Zalachoras, Ioannis, Evers, Melvin M., van Roon-Mom, Willeke M. C., Aartsma-Rus, Annemieke M., Meijer, Onno C.

Journal:

Frontiers in Molecular Neuroscience

Year:

2011

Language:

english

File:

PDF, 749 KB

english, 2011

7

L5 Pre-clinical evaluation of aav5-mihtt gene therapy of huntington’s disease in rodents

Miniarikova, Jana, Zanella, Ilaria, Blits, Bas, Evers, Melvin, Zimmer, Virginie, Spoerl, Alexia, Southwell, Amber, Hayden, Michael, Deventer, Sander van, Deglon, Nicole, Petry, Harald, Konstantinova,

Journal:

Journal of Neurology Neurosurgery & Psychiatry

Year:

2016

Language:

english

File:

PDF, 77 KB

english, 2016

8

Preventing Formation of Toxic N-Terminal Huntingtin Fragments Through Antisense Oligonucleotide-Mediated Protein Modification

Evers, Melvin M., Tran, Hoang-Dai, Zalachoras, Ioannis, Meijer, Onno C., den Dunnen, Johan T., van Ommen, Gert-Jan B., Aartsma-Rus, Annemieke, van Roon-Mom, Willeke M.C.

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2014

Language:

english

File:

PDF, 381 KB

english, 2014

9

A unique residue in rab3c determines the interaction with novel binding protein Zwint-1

Thijs van Vlijmen, Mathijs Vleugel, Melvin Evers, Shabaz Mohammed, Phebe S. Wulf, Albert J.R. Heck, Casper C. Hoogenraad, Peter van der Sluijs

Journal:

Year:

2008

Language:

english

File:

PDF, 503 KB

english, 2008

10

LETTERS TO THE EDITOR

Bernard Bellush, Melvin I. Urofsky and Alf Evers

Journal:

New York History

Year:

1966

Language:

english

File:

PDF, 236 KB

english, 1966

11

CT sialography: utilising acinar filling

Evers, Kathryn, Zito, Joseph L., Fine, Jeffrey, Leeds, Melvin, Moss, Lawrence J.

Journal:

British Journal of Radiology

Year:

1985

Language:

english

File:

PDF, 1.08 MB

english, 1985

12

Antisense oligonucleotides in therapy for neurodegenerative disorders

Evers, Melvin M., Toonen, Lodewijk J.A., van Roon-Mom, Willeke M.C.

Journal:

Advanced Drug Delivery Reviews

Year:

2015

Language:

english

File:

PDF, 816 KB

english, 2015

13

A Perspective on Organoids for Virology Research

Sridhar, Adithya, Simmini, Salvatore, Ribeiro, Carla M. S., Tapparel, Caroline, Evers, Melvin M., Pajkrt, Dasja, Wolthers, Katja

Journal:

Year:

2020

File:

PDF, 239 KB

2020

14

Making (anti-) sense out of huntingtin levels in Huntington disease

Evers, Melvin M, Schut, Menno H, Pepers, Barry A, Atalar, Melek, van Belzen, Martine J, Faull, Richard LM, Roos, Raymund AC, van Roon-Mom, Willeke MC

Journal:

Molecular Neurodegeneration

Year:

2015

Language:

english

File:

PDF, 1.03 MB

english, 2015

15

Ataxin-3 protein modification as a treatment strategy for spinocerebellar ataxia type 3: Removal of the CAG containing exon

Evers, Melvin M., Tran, Hoang-Dai, Zalachoras, Ioannis, Pepers, Barry A., Meijer, Onno C., den Dunnen, Johan T., van Ommen, Gert-Jan B., Aartsma-Rus, Annemieke, van Roon-Mom, Willeke M.C.

Journal:

Neurobiology of Disease

Year:

2013

Language:

english

File:

PDF, 1.22 MB

english, 2013

16

Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Toonen, Lodewijk J. A., Overzier, Maurice, Evers, Melvin M., Leon, Leticia G., van der Zeeuw, Sander A. J., Mei, Hailiang, Kielbasa, Szymon M., Goeman, Jelle J., Hettne, Kristina M., Magnusson, Olafur

Journal:

Molecular Neurodegeneration

Year:

2018

Language:

english

File:

PDF, 1.46 MB

english, 2018

17

AAV5-miHTT lowers huntingtin mRNA and protein without off-target effects in patient-derived neuronal cultures and astrocytes

Keskin, Sonay, Brouwers, Cynthia C., Sogorb-Gonzalez, Marina, Martier, Raygene, Depla, Josse A., Vallès, Astrid, van Deventer, Sander J., Konstantinova, Pavlina, Evers, Melvin M.

Journal:

Molecular Therapy — Methods & Clinical Development

Year:

2019

File:

PDF, 2.21 MB

2019

18

[BMJ Publishing Group Ltd EHDN 2018 Plenary Meeting, Vienna, Austria, Programme and Abstracts - ()] Experimental therapeutics â preclinical - I04âAAV5-MIHTT gene therapy demonstrates broad distribution and strong human mutant huntingtin lowering in a huntington disease minipig model

Klima, Jiri, Evers, Melvin M, Miniarikova, Jana, Juhas, Stefan, VallÃ¨s, Astrid, Bohuslavova, Bozena, Juhasova, Jana, Skalnikova, Helena Kupcova, Vodicka, Petr, Valekova, Ivona, Brouwers, Cynthia, Bli

Year:

2018

File:

PDF, 56 KB

2018

19

Artificial MicroRNAs Targeting C9orf72 Can Reduce Accumulation of Intra-nuclear Transcripts in ALS and FTD Patients

Martier, Raygene, Liefhebber, Jolanda M., Miniarikova, Jana, van der Zon, Tom, Snapper, Jolanda, Kolder, Iris, Petry, Harald, van Deventer, Sander J., Evers, Melvin M., Konstantinova, Pavlina

Journal:

Molecular Therapy — Nucleic Acids

Year:

2019

File:

PDF, 2.81 MB

2019

20

AAV5-miHTT gene therapy for Huntington disease: lowering both huntingtins

Evers, Melvin M., Konstantinova, Pavlina

Journal:

Expert Opinion on Biological Therapy

Year:

2020

File:

PDF, 453 KB

2020

21

SYSTEMIC PHARMACOKINETICS AND PHARMACODYNAMICS OF INTRAVITREAL AFLIBERCEPT, BEVACIZUMAB, AND RANIBIZUMAB

Avery, Robert L., Castellarin, Alessandro A., Steinle, Nathan C., Dhoot, Dilsher S., Pieramici, Dante J., See, Robert, Couvillion, Stephen, Nasir, Maʼan A., Rabena, Melvin D., Maia, Mauricio, Van Ever

Journal:

Year:

2017

Language:

english

File:

PDF, 920 KB

english, 2017

22

L4 Sustained and strong HTT silencing by AAV5-miHTT as therapy for huntington’s disease

Evers, Melvin, Miniarikova, Jana, Blits, Bas, Spronck, Lisa, Brouwers, Cynthia, Déglon, Nicole, Motlik, Jan, Bankiewicz, Krystof, Southwell, Amber, Haan, Martin de, Richard, Charles, Petry, Harald, Ko

Journal:

Journal of Neurology Neurosurgery & Psychiatry

Year:

2016

Language:

english

File:

PDF, 65 KB

english, 2016

23

Artificial MicroRNAs Targeting C9orf72 Can Reduce Accumulation of Intra-nuclear Transcripts in ALS and FTD Patients

Martier, Raygene, Liefhebber, Jolanda M., Miniarikova, Jana, van der Zon, Tom, Snapper, Jolanda, Kolder, Iris, Petry, Harald, van Deventer, Sander J., Evers, Melvin M., Konstantinova, Pavlina

Journal:

Molecular Therapy — Nucleic Acids

Year:

2019

Language:

english

File:

PDF, 2.81 MB

english, 2019

24

Ataxin-3 Protein and RNA Toxicity in Spinocerebellar Ataxia Type 3: Current Insights and Emerging Therapeutic Strategies

Evers, Melvin M., Toonen, Lodewijk J. A., Roon-Mom, Willeke M. C.

Journal:

Molecular Neurobiology

Year:

2014

Language:

english

File:

PDF, 539 KB

english, 2014

25

In vivo proof-of-concept of removal of the huntingtin caspase cleavage motif-encoding exon 12 approach in the YAC128 mouse model of Huntington’s disease

Casaca-Carreira, João, Toonen, Lodewijk J.A., Evers, Melvin M., Jahanshahi, Ali, van-Roon-Mom, Willeke M.C., Temel, Yasin

Journal:

Biomedicine & Pharmacotherapy

Year:

2016

Language:

english

File:

PDF, 742 KB

english, 2016

26

AAV5-miHTT lowers huntingtin mRNA and protein without off-target effects in patient-derived neuronal cultures and astrocytes

Keskin, Sonay, Brouwers, Cynthia C., Sogorb-Gonzalez, Marina, Martier, Raygene, Depla, Josse A., Vallès, Astrid, van Deventer, Sander J., Konstantinova, Pavlina, Evers, Melvin M.

Journal:

Molecular Therapy — Methods & Clinical Development

Year:

2019

Language:

english

File:

PDF, 2.21 MB

english, 2019

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